1
The sky is blue... duh!
When someone states an obvious fact like the sky being blue, you can sign 'sky blue' and follow it up with the 'duh' sign. Make sure to use a highly sarcastic facial expression to emphasize that everyone already knows this information.
2
Did you know water is wet? Duh.
After someone asks a silly or obvious question, you can respond by throwing up your hands into the 'duh' position. Your face should look completely unimpressed, with a twisted mouth and tilted head, to show how ridiculous the question is.
3
Obviously, we need to study for the test. Duh!
You can use this sign at the end of a sentence to mean 'obviously.' Sign that you need to study, and finish with 'duh,' emphasizing the obviousness with a strong head tilt and hands brought up to your chest.