1
We learned about chemical reactions in class.
Sign 'chemical' with the alternating 'C' handshapes, then follow up with the signs for 'reaction' and 'class'. This establishes the topic clearly for your conversational partner.
2
This cleaning spray has a lot of chemicals.
Point to the spray bottle to establish the subject, sign 'many', and then use the alternating 'C' handshapes for 'chemicals'. Your facial expression can emphasize the large quantity.
3
Are there chemicals in this food?
Raise your eyebrows and lean forward slightly to indicate a yes/no question. Sign 'food', 'have', and finally use the alternating 'C' handshapes to ask if chemicals are present.